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Benzene lab: stability, substitution and aspirin

Aspirin, dyes and many medicines are built on the benzene ring. Find out why this ring is so stable and how chemists make a medicine from it.

💊stabilisation 152 kJ/molbenzene, phenol and aspirin
LevelS6 (and A Level)
TimeAbout 35 min
You useEnthalpy, moles, % yield
PriceFree: no account

🎯 Aim

To investigate the stability of benzene, its substitution reactions and the yield of an aromatic synthesis.

You will learn to

  • Use enthalpy data to show benzene is stabilised.
  • Describe electrophilic substitution reactions and their conditions.
  • Explain why phenol reacts more readily than benzene.
  • Calculate theoretical and percentage yields.

🧭 What to do

  1. Read the enthalpy graph and the stabilisation energy.
  2. Choose each Reaction and read its conditions and electrophile.
  3. Set the mass of salicylic acid and of aspirin obtained.
  4. Read the percentage yield.
  5. Answer the questions with the class data.
  6. Write your conclusion and download your lab report.

🔬 Lab bench

📋 The data

Enthalpies of hydrogenation.

🧠 Investigate: answer from the data

Type your answer and tap Check. Use 💡 Hint first; open the method only when you are stuck.

📄 My lab report

Your report collects the aim, your data table, the graphs, your answers and your conclusion. It is made on your phone or computer: nothing is sent to anyone.

Check your conclusion

Benzene releases 152 kJ/mol less energy on hydrogenation than three C=C bonds would, because its π electrons are delocalised; it therefore undergoes substitution, not addition, with strong electrophiles and catalysts. The OH group of phenol activates the ring. Aspirin is made from salicylic acid; yields below 100 % come from losses in purification.

➕ Get more from this experiment

📝 Free

Print the worksheet (button above), download the data, and save your report. Teachers can project this page in class.

📦 Premium Lab Pack

1 000 RWF

  • Worksheet: the synthesis of aspirin (method and yield record)
  • Aromatic chemistry problems
  • Teacher guide and answer key
  • Exam-style questions with marking scheme

👩‍🏫 For teachers

Use it as a practical when apparatus is missing, as homework, or as a project. Free lesson plans help you plan, teach and assess.

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